Safety First!

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Caregiver resources

Caregivers play an important role in the fight against metastatic non-small cell lung cancer or advanced-stage pancreatic cancer

Who is a caregiver?

Some caregivers are family members, friends, or simply others who provide you with needed support. Giving care might mean being there to help with day-to-day activities, such as going to medical visits or preparing meals. A caregiver can also support you emotionally by talking, listening, and helping you work through challenges.

Changing roles, changing feelings

A caregiver is often an active part of someone’s life before cancer. But living with the disease can change the roles that you are used to. A caregiver may have to take on new responsibilities. Stress and confusion are normal at this time. Seeking help from a counselor or psychologist can help.

Dealing with ups and downs

Many caregivers say they have a range of strong emotions that seem to come and go during the disease journey. The hopeful highs and the depressing lows can feel like being on a roller coaster. Sadness, fear, hope, anger, hopelessness, worry, grief—all these feelings are normal and are felt by many caregivers. As a caregiver, you may want to reach out to one of the organizations below.

Genentech, Inc. and Astellas Pharma US, Inc. do not control or endorse the content of the third-party websites listed here. The information provided by these organizations is meant for informational purposes only and is not meant to replace a physician's medical advice. By selecting any of the links below, you will be leaving

Family Caregiver Alliance (FCA)
(800) 445-8106

Caregiver Action Network
(202) 454-3970

Tips for caregivers on taking care of themselves

Caregivers often put their own needs and feelings aside. But they need to stay healthy physically and mentally. It’s important for them to care for themselves and let others help them, too. With help from others, a caregiver may be able to:

  • Stay active and as healthy as possible
  • Focus on the important things and let friends or family help with day-to-day tasks, such as food shopping or doing the laundry
  • Realize that it is okay to let go of responsibilities in areas where others have more experience or interest, such as legal or financial issues

Below are some tips for things you can do that might help you to restore the mind, body, and spirit. Always talk with your doctor before starting or increasing physical activity.

  • Exercise, do yoga, or meditate
  • Go for a walk or a drive
  • Read, rest, or take a nap
  • Work in the yard or keep up with a hobby


See Tarceva Important Safety Information

Who is Tarceva (erlotinib) for?

  • Tarceva is prescribed for patients with non-small cell lung cancer (NSCLC) whose cancer has spread to other parts of the body and that has certain types of epidermal growth factor receptor (EGFR) mutations. Your healthcare provider will perform a test to make sure that Tarceva is right for you.
  • It is not known if Tarceva is safe and effective in EGFR mutations other than those included in the FDA-approved prescribing information.
  • Tarceva is not meant to be used at the same time as certain types of chemotherapy for NSCLC.

Tarceva is approved for advanced-stage pancreatic cancer.

  • Tarceva in combination with gemcitabine is prescribed for patients with advanced-stage pancreatic cancer whose cancer has spread, grown, or cannot be surgically removed and who have not received previous chemotherapy.

Important Safety Information

Contact your HCP right away if you experience any of the side effects listed below.

What are the possible side effects of Tarceva?

Tarceva can cause serious side effects, including:

  • Lung problems (called interstitial lung disease [ILD] events). Tarceva has been shown to cause lung problems, including death. Symptoms of lung problems may include shortness of breath, cough, and fever. Tarceva may need to be stopped if you have any of these symptoms.
  • Liver and kidney problems. Tarceva has been shown to cause severe kidney and liver problems, including death. Some people had their kidneys and liver stop working. Let your HCP know if you have a history of liver or kidney disease.
  • Stomach and intestinal problems (called gastrointestinal [GI] perforation). Tarceva has been shown to cause GI perforation, which has led to death. A GI perforation is a hole that develops in your stomach or intestine. People may be at a higher risk for GI perforation if they:
    • Are taking medicines including those that may help block the growth of blood vessels; steroids; nonsteroidal anti-inflammatory drugs (NSAIDs); and certain chemotherapies. Always tell your HCP about any medicines you are taking.
    • Have a history of ulcers or other stomach disease.
  • Serious skin conditions. Tarceva has been shown to cause blistering and skin peeling. This may result in other serious skin disorders or death.
  • Blood, bleeding, and clotting problems. Tarceva has been shown to cause certain blood problems and other bleeding and clotting problems. These have led to stroke and death.
  • Eye disorders. Tarceva has been shown to cause dry eyes, unusual eyelash growth, or swelling of the cornea. The cornea is the clear coating of the eyeball. This swelling may irritate or damage the eye.
  • Bleeding events when taking warfarin with Tarceva. Tell your HCP if you are taking a blood thinner, such as warfarin. Taking Tarceva with this medicine can cause death.
  • Pregnancy. Tarceva can harm an unborn baby. Women should use effective birth control during treatment and for at least 1 month after the last dose of Tarceva. Tell your HCP if you have become pregnant, or if you think you may be pregnant, during treatment with Tarceva. Do not breast-feed during treatment with Tarceva and for 2 weeks after the final dose.

When should I call my HCP while taking Tarceva?

Call your HCP if you have:

  • Serious or ongoing diarrhea, nausea (feeling sick to your stomach), loss of appetite, or vomiting.
  • New or worsening shortness of breath or cough.
  • Eye irritation.
  • New or worsening rash, blistering, or peeling of the skin.
  • Any changes in smoking habits.

What are some of the most common side effects of Tarceva?

In 1st line NSCLC treatment:

  • Diarrhea
  • Weakness
  • Rash
  • Cough
  • Shortness of breath
  • Loss of appetite (not wanting to eat)

In pancreatic cancer treatment:

  • Fatigue (feeling very tired)
  • Rash
  • Nausea
  • Loss of appetite
  • Diarrhea

What should I know about skin (including rash), hair, and nail problems or diarrhea while taking Tarceva?

  • Skin (including rash):
    • While taking Tarceva, rash could happen or get worse if the skin is exposed to the sun. You may want to use alcohol-free lotions and sunscreens or avoid being out in the sun.
    • Your skin and nails may get darker. You may also have dry skin that may or may not crack. This most often happens with rash.
    • Talk with your HCP if you notice a rash. He or she may be able to help you manage it.
  • Hair and nails:
    • Hair and nail problems have been seen in patients taking Tarceva. These include increased hairiness and brittle or loose nails.
  • Diarrhea:
    • Diarrhea can usually be treated with antidiarrhea medicine. Your HCP can help you find the right medicine for you.

What should I do if I am taking or am prescribed other medicines or supplements while taking Tarceva?

  • Always tell your HCP about all of the medicines and herbal supplements you are taking.
  • DO NOT start taking any new medicines or herbal supplements before talking with your HCP.
  • DO NOT eat grapefruit or drink grapefruit juice before talking with your HCP.

Will smoking affect my treatment with Tarceva?

  • If you smoke, you should stop smoking before you start treatment with Tarceva.
  • If you continue to smoke, your treatment with Tarceva may need to be adjusted. Talk with your HCP if you continue to smoke.

Always talk with your HCP about any side effects you may have with Tarceva.

You may report side effects to the FDA at (800) FDA-1088 or You may also report side effects to Genentech at (888) 835-2555.

Please see the Tarceva full Prescribing Information for additional Important Safety Information.