Important Information to Know
Some rare, but possibly serious, side effects may occur with Tarceva.
In clinical studies, there were infrequent reports of lung injuries similar to Interstitial Lung Disease (ILD)-like events in patients receiving Tarceva for the treatment of Non-Small Cell Lung Cancer (NSCLC) or other advanced solid tumors. Reports of these ILD-like lung injuries have been serious and have included deaths in some patients.
Liver and/or kidney problems (including deaths) have been reported in some patients taking Tarceva. Let your doctor know if you have a history of liver or kidney disease.
Tarceva may cause harm to an unborn baby or may cause possible risk of pregnancy loss. Women should avoid becoming pregnant and avoid breastfeeding while taking Tarceva.
Call your doctor right away if you have these signs or symptoms:
- New or worsening skin rash
- Serious or ongoing diarrhea, nausea, loss of appetite, or vomiting
- New or worsening shortness of breath or cough
- Fever
- Eye irritation
Before you start taking Tarceva
Clinical studies have shown that taking Tarceva with certain foods and other drugs may affect how well Tarceva may work for you. Let your doctor know if you are taking other prescription or over-the-counter drugs or herbal supplements. While taking Tarceva, do not start taking any new drugs or herbal supplements before talking to your doctor. Do not eat grapefruit or drink grapefruit juice while taking Tarceva. Tarceva may also affect other medications you are taking.
When taking Tarceva with some drugs, such as blood thinners (Coumadinư, warfarin), there may be an increased risk of bleeding.
If you smoke, you should stop smoking while taking Tarceva, as it may affect how well Tarceva works for you. If you continue to smoke, you should speak to your doctor before taking Tarceva.
Common side effects of Tarceva
Rash and diarrhea were the most common side effects associated with Tarceva in a large clinical study. You may also have other changes in your skin.
The rash associated with Tarceva therapy may appear on your body or face, typically within 8 days of starting this treatment. However, the rash may occur anytime during treatment with Tarceva.
The rash is not an allergic reaction. It may look like acne or dry skin. It is not acne. Talk to your doctor if a rash occurs.
Typically, diarrhea may develop within 12 days of starting Tarceva.
Hair and nail changes have been seen with Tarceva.
Always let your doctor or nurse know if you experience any side effects. Ask your doctor or nurse for the best way to handle drug-related side effects.
Tarceva is not right for everyone. Ask your doctor if once-daily Tarceva is right for you.
are trademarks of OSI Pharmaceuticals, Inc.
